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Description
Lifitegrast, also known as SAR-1118, is an LFA-1 antagonist intended for the treatment of vascular complications of the eye. Lifitegrast inhibits T cell-mediated inflammation by blocking the binding of two important cell surface proteins (lymphocyte function-associated antigen 1 and intercellular adhesion molecule 1), thus lessening overall inflammatory responses. 
Chemical Structure
 
Chemical Name
(S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 
SMILES Code
O=C(O)[C@@H](NC(C1=C(Cl)C2=C(CN(C(C3=CC=C4C=COC4=C3)=O)CC2)C=C1Cl)=O)CC5=CC=CC(S(=O)(C)=O)=C5 
Theoretical Analysis
XingMo Cat#:XM702 
Product Name:Lifitegrast 
Synonyms:SAR-1118; SAR 1118; SAR1118; Lifitegrast, brand name: Xiidra. 
CAS#:1025967-78-5 
Chemical Formula:C29H24Cl2N2O7S 
Exact Mass:614.0681 
Molecular Weight:615.478 
Technical Data

Appearance: Solid powder

Purity: >98%

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4o for short term (days to weeks) or -20oC for long term (months to years).

Solubility: Soluble in DMSO, not in water

 



WARNING: This product is for research use only, not for human or veterinary use

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